Spatial and Non-spatial Stochastic Models for Immune Response
2008, v.14, Issue 2, 255-276
We propose both spatial and non-spatial stochastic models for pathogen dynamics in the presence of an immune response. One of our spatial models shows that, at least in theory, a pathogen may escape the immune system thanks to its high mutation probability alone. While one of our non-spatial models also exhibits this behavior, another behaves quite differently from the corresponding spatial model.
Keywords: mutation,immune system,branching process,spatial stochastic model,contact process